Nane is a Swedish lawyer and a maternal half-niece of Raoul Wallenberg, a renowned Swedish humanitarian, diplomat and businessman. She was born in Stockholm, where she grew up and studied law. After working as an assistant judge at the administrative and fiscal court of appeal, she joined the office of the UN High Commissioner for Refugees in Geneva in 1981.
Nane married Kofi Annan in 1984 and accompanied him to New York in his role as Secretary-General. Nane is involved in women’s issues and programs that aim at alleviating poverty and the welfare of children, refugees and the disabled.